Successful treatment with fingolimod of graft-versus-host disease of the central nervous system-Reference-Cited by-同舟云学术

Successful treatment with fingolimod of graft-versus-host disease of the central nervous system

Published:2018-01-02 Issue:1 Volume:2 Page:10-13
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Gauthier Jordan¹^ORCID,Vermersch Patrick²³,Chauvet Paul¹,Varlet Pauline⁴,Coiteux Valérie¹,Magro Leonardo¹,Yakoub-Agha Ibrahim¹⁵

Affiliation:

1. Allogeneic Stem Cell Transplantation Unit, Department of Hematology,

2. Department of Neurology, Salengro Hospital,

3. Unité Mixte de Recherche (UMR)–INSERM 1171, Fédératif Hospitalo-Universitaire (FHU) Imminent, University of Lille,

4. Laboratory of Immunology, Biology-Pathology Center, and

5. LIRIC-INSERM U995, FHU Imminent, University of Lille, Centre Hospitalier Universitaire (CHU) Lille, Lille, France

Abstract

Key Points Fingolimod could be efficient to treat GVHD of the central nervous system. Further research should explore the use of fingolimod and other sphingosine-1-phosphate receptor agonists to prevent or treat GVHD.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/1/10/879653/advances011478.pdf

Reference16 articles.

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3. FTY720 ameliorates murine sclerodermatous chronic graft-versus-host disease by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin;Huu;Arthritis Rheum,2013

4. The S1P1 receptor-selective agonist CYM-5442 reduces the severity of acute GVHD by inhibiting macrophage recruitment;Cheng;Cell Mol Immunol,2015

5. The mini-mental state examination: a comprehensive review;Tombaugh;J Am Geriatr Soc,1992

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