FTY720 Ameliorates Murine Sclerodermatous Chronic Graft-Versus-Host Disease by Promoting Expansion of Splenic Regulatory Cells and Inhibiting Immune Cell Infiltration Into Skin

Author:

Huu Doanh Le1,Matsushita Takashi1,Jin Guihua1,Hamaguchi Yasuhito1,Hasegawa Minoru1,Takehara Kazuhiko1,Fujimoto Manabu1

Affiliation:

1. Kanazawa University; Kanazawa; Japan

Publisher

Wiley

Subject

Pharmacology (medical),Immunology,Rheumatology,Immunology and Allergy

Reference50 articles.

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2. Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network;Rosen;Nat Rev Immunol,2005

3. Role of sphingosine 1-phosphate receptor type 1 in lymphocyte egress from secondary lymphoid tissues and thymus;Chiba;Cell Mol Immunol,2006

4. Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720;Zemann;Blood,2006

5. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1;Matloubian;Nature,2004

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