The impact of response kinetics for multiple myeloma in the era of novel agents-Reference-Cited by-同舟云学术

The impact of response kinetics for multiple myeloma in the era of novel agents

Published:2019-10-08 Issue:19 Volume:3 Page:2895-2904
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Yan Yuting¹,Mao Xuehan¹,Liu Jiahui¹,Fan Huishou¹,Du Chenxing¹,Li Zengjun¹,Yi Shuhua¹,Xu Yan¹,Lv Rui¹,Liu Wei¹,Deng Shuhui¹,Sui Weiwei¹,Wang Qi¹,Zou Dehui¹,Wang Jianxiang¹,Cheng Tao¹,Zhan Fenghuang²,Tai Yu-Tzu³,Yuan Chenglu⁴,Du Xin⁵,Qiu Lugui¹,Anderson Kenneth C.³,An Gang¹⁴⁵

Affiliation:

1. State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, China;

2. Division of Hematology, Oncology, and Blood and Marrow Transplantation, Department of Internal Medicine, University of Iowa, Iowa City, IA;

3. LeBow Institute for Myeloma Therapeutics and Jerome Lipper Center for Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA;

4. Qilu Hospital of Shandong University (Qing dao), Qingdao, China; and

5. Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China

Abstract

Key Points Early responders with MM (TBR ≤3 months) are more likely to have higher lactate dehydrogenase levels and experience inferior outcomes. The kinetic pattern of response is a simple and powerful predictor for survival of patients with MM even in the era of novel agents.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/3/19/2895/1223953/advancesadv2019000432.pdf

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