Comprehensive mutational profiling of core binding factor acute myeloid leukemia-Reference-Cited by-同舟云学术

Comprehensive mutational profiling of core binding factor acute myeloid leukemia

Published:2016-05-19 Issue:20 Volume:127 Page:2451-2459
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Duployez Nicolas¹²,Marceau-Renaut Alice¹²,Boissel Nicolas³,Petit Arnaud⁴,Bucci Maxime¹,Geffroy Sandrine¹²,Lapillonne Hélène⁵,Renneville Aline¹²,Ragu Christine⁴,Figeac Martin⁶,Celli-Lebras Karine³,Lacombe Catherine⁷,Micol Jean-Baptiste⁸⁹,Abdel-Wahab Omar⁹,Cornillet Pascale¹⁰,Ifrah Norbert¹¹,Dombret Hervé³,Leverger Guy⁴,Jourdan Eric¹²,Preudhomme Claude¹²

Affiliation:

1. Biology and Pathology Center, Laboratory of Hematology, Centre Hospitalier Universitaire (CHU) Lille, Lille, France;

2. Cancer Research Institute, INSERM Unité Mixte de Recherche (UMR)–S 1172, Lille, France;

3. Department of Hematology, Saint Louis Hospital, Assistance Publique–Hôpitaux de Paris (AP-HP), Paris, France;

4. Department of Pediatric Hematology and Oncology, Trousseau Hospital, AP-HP, Paris, France;

5. Laboratory of Hematology, Trousseau Hospital, AP-HP, Paris, France;

6. Functional and Structural Genomic Platform, Lille University, Lille, France;

7. Goelamsthèque, Cochin Hospital, AP-HP, Paris, France;

8. Department of Hematology, Gustave Roussy Institute, INSERM UMR 1170, Villejuif, France;

9. Human Oncology and Pathogenesis Program and Leukemia Service, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, New York, NY;

10. Laboratory of Hematology, CHU Reims, Reims, France;

11. Department of Hematology, CHU Angers, Angers, France; and

12. Department of Hematology, CHU Nîmes, Nîmes, France

Abstract

Key Points Recurrent mutations in chromatin modifiers and cohesin were observed in t(8;21) AML, but not inv(16) AML. t(8;21) AML patients with mutations in kinase signaling plus chromatin modifiers or cohesin members had the highest risk of relapse.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/20/2451/1393099/2451.pdf

Reference51 articles.

1. The influence of age on prognosis of de novo acute myeloid leukemia differs according to cytogenetic subgroups.;Schoch;Haematologica,2004

2. Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet.;Döhner;Blood,2010

3. Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.;Jourdan;Blood,2013

4. Individual patient data-based meta-analysis of patients aged 16 to 60 years with core binding factor acute myeloid leukemia: a survey of the German Acute Myeloid Leukemia Intergroup.;Schlenk;J Clin Oncol,2004

5. The clinical spectrum of adult acute myeloid leukaemia associated with core binding factor translocations.;Appelbaum;Br J Haematol,2006

Cited by 187 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evolution of transcriptomic profiles in relapsed inv(16) acute myeloid leukemia;Leukemia Research;2024-10

2. Minimal Requirements for Cancer Initiation: A Comparative Consideration of Three Prototypes of Human Leukemia;Cancers;2024-09-09

3. Mutational cooperativity of RUNX1::RUNX1T1 isoform 9a and oncogenic NRAS in zebrafish myeloid leukaemia;Biology Open;2024-08-30

4. Molecular profiling of acute myeloid leukemia with Runx1-Runx1t1 fusion;Alexandria Journal of Medicine;2024-08-28

5. Real‐world outcomes of intensive induction approaches in core binding factor acute myeloid leukemia;eJHaem;2024-07-24