Chimerism levels after stem cell transplantation are primarily determined by the ratio of donor to host stem cells
Author:
Affiliation:
1. Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
2. Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/117/16/4400/1336653/zh801611004400.pdf
Reference5 articles.
1. Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches.;Czechowicz;Science,2007
2. Niche recycling through division-independent egress of hematopoietic stem cells.;Bhattacharya;J Exp Med,2009
3. Hematopoietic stem cells engraft in mice with absolute efficiency.;Benveniste;Nat Immunol,2003
4. Persisting NK cell alloreactivity in the presence of long-term stable hematopoietic chimerism.;Westerhuis;Exp Hematol,2009
5. Long-term mixed chimerism after immunologic conditioning and MHC-mismatched stem-cell transplantation is dependent on NK-cell tolerance.;Westerhuis;Blood,2005
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