Numerous niches for hematopoietic stem cells remain empty during homeostasis-Reference-Cited by-同舟云学术

Numerous niches for hematopoietic stem cells remain empty during homeostasis

Published:2017-04-13 Issue:15 Volume:129 Page:2124-2131
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Shimoto Manabu¹²,Sugiyama Tatsuki¹³,Nagasawa Takashi¹³

Affiliation:

1. Department of Immunobiology and Hematology, Institute for Frontier Medical Sciences, and

2. Department of Primary Care and Emergency Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan; and

3. Laboratory of Stem Cell Biology and Developmental Immunology, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Osaka, Japan

Abstract

Key Points Numerous empty HSC niches, located distantly from filled niches, are available for engraftment and proliferation in bone marrow. Presumptive niches for granulocyte/macrophage progenitors appear to be filled in bone marrow.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/15/2124/1399578/blood740563.pdf

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4. Control of hematopoietic stem cells by the bone marrow stromal niche: the role of reticular cells;Nagasawa;Trends Immunol,2011

5. The bone marrow at the crossroads of blood and immunity;Mercier;Nat Rev Immunol,2011

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