Endothelial cells translate pathogen signals into G-CSF–driven emergency granulopoiesis-Reference-Cited by-同舟云学术

Endothelial cells translate pathogen signals into G-CSF–driven emergency granulopoiesis

Published:2014-08-28 Issue:9 Volume:124 Page:1393-1403
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Boettcher Steffen¹,Gerosa Rahel C.¹,Radpour Ramin¹,Bauer Judith²,Ampenberger Franziska³,Heikenwalder Mathias²,Kopf Manfred³,Manz Markus G.¹

Affiliation:

1. Division of Hematology, University Hospital Zurich, Zurich, Switzerland;

2. Institute for Virology, Technical University Munich/Helmholtz Center Munich, Munich, Germany; and

3. Institute for Molecular Health Sciences, Molecular Biomedicine, Swiss Federal Institute of Technology Zurich, Zurich, Switzerland

Abstract

Key Points ECs express Tlr4 and Myd88 and, after in vivo LPS or E coli stimulation, are the prime sources of G-CSF. ECs are sensors of systemically spread pathogens and subsequent drivers of BM emergency granulopoiesis.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/9/1393/1382854/1393.pdf

Reference59 articles.

1. Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization.;Lieschke;Blood,1994

2. Neutrophil recruitment and function in health and inflammation.;Kolaczkowska;Nat Rev Immunol,2013

3. Activation of hypoxia-inducible factor-1α (Hif-1α) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model.;Elks;Blood,2011

4. Resolution of inflammation by retrograde chemotaxis of neutrophils in transgenic zebrafish.;Mathias;J Leukoc Biol,2006

5. The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo.;Woodfin;Nat Immunol,2011

Cited by 226 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The granulocyte colony-stimulating factor produced during Streptococcus suis infection controls neutrophil recruitment in the blood without affecting bacterial clearance;Frontiers in Immunology;2024-08-02

2. Kmt2c restricts G-CSF-driven HSC mobilization and granulocyte production in a methyltransferase-independent manner;Cell Reports;2024-08

3. Mitochondrial perturbations in low-protein-diet-fed mice are associated with altered neutrophil development and effector functions;Cell Reports;2024-08

4. Exploring extramedullary hematopoiesis: unraveling the hematopoietic microenvironments;Frontiers in Hematology;2024-05-28

5. Mesenchymal stem cell-derived S100A8 facilitates leukemia stem cell maintenance via TLR4/PI3K/Akt signaling;2024-05-14