Phase 2 study of imexon, a prooxidant molecule, in relapsed and refractory B-cell non-Hodgkin lymphoma-Reference-Cited by-同舟云学术

Phase 2 study of imexon, a prooxidant molecule, in relapsed and refractory B-cell non-Hodgkin lymphoma

Published:2014-08-21 Issue:8 Volume:124 Page:1259-1265
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Barr Paul M.¹,Miller Thomas P.²,Friedberg Jonathan W.¹,Peterson Derick R.¹,Baran Andrea M.¹,Herr Megan¹,Spier Catherine M.³,Cui Haiyan²,Roe Denise J.²,Persky Daniel O.²,Casulo Carla¹,Littleton Jamie¹,Schwartz Mark⁴,Puvvada Soham²,Landowski Terry H.²,Rimsza Lisa M.³,Dorr Robert T.²,Fisher Richard I.⁵,Bernstein Steven H.¹,Briehl Margaret M.³

Affiliation:

1. University of Rochester, Wilmot Cancer Center, Rochester, NY;

2. University of Arizona Cancer Center, Tucson, AZ;

3. Department of Pathology, University of Arizona, Tucson, AZ;

4. HTG Molecular Diagnostics, Inc., Tucson, AZ; and

5. Fox Chase Cancer Center, Temple University, Philadelphia, PA

Abstract

Key Points Clinical responsiveness to imexon represents the first demonstration of efficacy with modulating cellular redox in B-cell NHL. Antioxidant-related gene expression predicted for response to imexon.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/8/1259/1382245/1259.pdf

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