High-dose dexamethasone vs prednisone for treatment of adult immune thrombocytopenia: a prospective multicenter randomized trial

Author:

Wei Yu1,Ji Xue-bin1,Wang Ya-wen1,Wang Jing-xia2,Yang En-qin3,Wang Zheng-cheng4,Sang Yu-qi5,Bi Zuo-mu6,Ren Cui-ai7,Zhou Fang8,Liu Guo-qiang9,Peng Jun110,Hou Ming111

Affiliation:

1. Department of Hematology, Qilu Hospital, Shandong University, Jinan, China;

2. Department of Hematology, Liaocheng People's Hospital, Liaocheng, China;

3. Department of Hematology, People's Hospital of Rizhao, Rizhao, China;

4. Department of Hematology, Central Hospital of Zibo, Zibo, China;

5. Department of Hematology, Heze Municipal Hospital, Heze, China;

6. Department of Hematology, Zibo First Hospital, Zibo, China;

7. Department of Hematology, Weifang People's Hospital, Weifang, China;

8. Department of Hematology, Jinan Military General Hospital, Jinan, China;

9. Department of Hematology, Shengli Oilfield General Hospital, Dongying, China;

10. Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, China; and

11. Shandong Provincial Key Laboratory of Immunohematology, Qilu Hospital, Shandong University, Jinan, China

Abstract

Key Points HD-DXM is a preferred strategy to conventional prednisone as first-line management of newly diagnosed adult primary ITP.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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