Long-term treatment follow-up of children with sickle cell disease monitored with abnormal transcranial Doppler velocities-Reference-Cited by-同舟云学术

Long-term treatment follow-up of children with sickle cell disease monitored with abnormal transcranial Doppler velocities

Published:2016-04-07 Issue:14 Volume:127 Page:1814-1822
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Bernaudin Françoise¹²,Verlhac Suzanne¹³,Arnaud Cécile¹²,Kamdem Annie¹²,Hau Isabelle²,Leveillé Emmanuella¹²,Vasile Manuela³,Kasbi Florence³,Madhi Fouad²,Fourmaux Christine²,Biscardi Sandra²,Gluckman Eliane⁴,Socié Gérard⁴,Dalle Jean-Hugues⁵,Epaud Ralph²⁶,Pondarré Corinne¹²⁶

Affiliation:

1. Referral Center for Sickle Cell Disease,

2. Department of Pediatrics, and

3. Medical Imaging Department, Centre Hospitalier Intercommunal de Créteil, Université Paris-Est Créteil Val de Marne, Créteil, France;

4. Department of Hematology, Saint-Louis Hospital and

5. Department of Pediatric Hematology, Robert Debré Hospital, Paris Diderot University, Paris, France; and

6. INSERM Unité 955, Université Paris-Est Créteil Val de Marne, Créteil, France

Abstract

Key PointsChildren with normalized TCD on transfusions were safely switched to hydroxyurea treatment, but trimestrial Doppler follow-up is required. Allogeneic transplant allowed the safe stop of transfusions in all patients, even in those with abnormal velocities before transplant.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/14/1814/1392824/1814.pdf

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4. Long-term stroke risk in children with sickle cell disease screened with transcranial Doppler.;Adams;Ann Neurol,1997

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