Composite end point of graft-versus-host disease-free, relapse-free survival after allogeneic hematopoietic cell transplantation

Author:

Holtan Shernan G.1,DeFor Todd E.2,Lazaryan Aleksandr1,Bejanyan Nelli1,Arora Mukta1,Brunstein Claudio G.1,Blazar Bruce R.1,MacMillan Margaret L.1,Weisdorf Daniel J.1

Affiliation:

1. Blood and Marrow Transplant Program, and

2. Biostatistics and Informatics Core, Masonic Cancer Center, University of Minnesota, Minneapolis, MN

Abstract

Key Points GRFS is a new composite end point useful for comparing HCT techniques and represents ideal post-HCT recovery. In our cohort of 907 allogeneic HCT recipients, 1-year GRFS was 31%, with best outcomes in recipients of marrow from matched sibling donors.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference21 articles.

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