Use of composite endpoints in clinical trials
Author:
Affiliation:
1. Biometrics; Vertex Pharmaceuticals; Boston MA U.S.A.
2. Boston University; Boston MA U.S.A.
Publisher
Wiley
Subject
Statistics and Probability,Epidemiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/sim.6205/fullpdf
Reference30 articles.
1. Committee for Proprietary Medicinal Products Points to consider on multiplicity issues in clinical trials 2002 http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003640.pdf
2. Some issues with composite endpoints in clinical trials;Chi;Fundamental & Clinical Pharmacology,2005
3. Multiple Analyses in Clinical Trials
4. Combined endpoints: can we use them?;Lubsen;Statistics in Medicine,2002
5. Perspectives on composite endpoints;Cannon;Controlled Clinical Trials,1997
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