hGH promotes megakaryocyte differentiation and exerts a complementary effect with c-Mpl ligands on thrombopoiesis-Reference-Cited by-同舟云学术

hGH promotes megakaryocyte differentiation and exerts a complementary effect with c-Mpl ligands on thrombopoiesis

Published:2014-04-03 Issue:14 Volume:123 Page:2250-2260
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Xu Yang¹,Wang Song¹,Shen Mingqiang¹,Zhang Zhou¹,Chen Shilei¹,Chen Fang¹,Chen Mo¹,Zeng Dongfeng¹²,Wang Aiping¹,Zhao Jinghong³,Cheng Tianmin¹,Su Yongping¹,Wang Junping¹

Affiliation:

1. Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine,

2. Department of Hematology, and

3. Department of Nephrology, Xinqiao Hospital, Third Military Medical University, Chongqing, China

Abstract

Key Points hGH has a distinct capacity to promote the differentiation, especially the terminal differentiation of human primary megakaryocytes. hGH exerts a complementary and synergistic effect with c-Mpl ligands on thrombopoiesis.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/14/2250/1375651/2250.pdf

Reference53 articles.

1. Growth hormone signalling and its regulation: preventing too much of a good thing.;Frank;Growth Horm IGF Res,2001

2. Immunologic and hematologic effects of neuroendocrine hormones. Studies on DW/J dwarf mice.;Murphy;J Immunol,1992

3. Growth hormone exerts hematopoietic growth-promoting effects in vivo and partially counteracts the myelosuppressive effects of azidothymidine.;Murphy;Blood,1992

4. Recombinant human growth hormone promotes hematopoietic reconstitution after syngeneic bone marrow transplantation in mice.;Tian;Stem Cells,1998

5. Age- and irradiation-associated loss of bone marrow hematopoietic function in mice is reversed by recombinant human growth hormone.;Carlo-Stella;Exp Hematol,2004

Cited by 32 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. 3D skin bioprinting as promising therapeutic strategy for radiation‐associated skin injuries;Wound Repair and Regeneration;2024-04-11

2. Discovery of a novel FLT3 agonist for the treatment of thrombocytopenia using AI-based virtual screening;2023-09-20

3. Xanthotoxin, a novel inducer of platelet formation, promotes thrombocytopoiesis via IL-1R1 and MEK/ERK signaling;Biomedicine & Pharmacotherapy;2023-07

4. The Application of Ethnomedicine in Modulating Megakaryocyte Differentiation and Platelet Counts;International Journal of Molecular Sciences;2023-02-05

5. Akt-mediated mitochondrial metabolism regulates proplatelet formation and platelet shedding post vasopressin exposure;Journal of Thrombosis and Haemostasis;2023-02