Redirecting traffic using the XPO1 police
Author:
Affiliation:
1. UNIVERSITY OF GLASGOW
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/122/17/2926/1369762/2926.pdf
Reference8 articles.
1. Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias.;Walker;Blood,2013
2. CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications [published online ahead of print April 16, 2013].;Tai;Leukemia
3. KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia.;Etchin;Br J Haematol,2013
4. Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia.;Lapalombella;Blood,2012
5. Nuclear export of proteins and drug resistance in cancer.;Turner;Biochem Pharmacol,2012
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4. XPO1 Inhibitor Selinexor Overcomes Intrinsic Ibrutinib Resistance in Mantle Cell Lymphoma via Nuclear Retention of IκB;Molecular Cancer Therapeutics;2018-12
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