MUC1-mediated induction of myeloid-derived suppressor cells in patients with acute myeloid leukemia-Reference-Cited by-同舟云学术

MUC1-mediated induction of myeloid-derived suppressor cells in patients with acute myeloid leukemia

Published:2017-03-30 Issue:13 Volume:129 Page:1791-1801
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Pyzer Athalia Rachel¹^ORCID,Stroopinsky Dina¹,Rajabi Hasan²,Washington Abigail¹,Tagde Ashujit²,Coll Maxwell¹,Fung Jacqueline³,Bryant Mary Paty¹,Cole Leandra¹,Palmer Kristen¹,Somaiya Poorvi¹,Karp Leaf Rebecca¹,Nahas Myrna¹,Apel Arie¹,Jain Salvia¹,McMasters Malgorzata¹,Mendez Lourdes¹,Levine James¹,Joyce Robin¹,Arnason Jon¹,Pandolfi Pier Paolo³,Kufe Donald²,Rosenblatt Jacalyn¹,Avigan David¹

Affiliation:

1. Department of Bone Marrow Transplantation, Beth Israel Deaconess Medical Center,

2. Dana Farber Cancer Institute, and

3. Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Harvard Medical School, Boston, MA

Abstract

Key Points MDSCs are expanded in AML and contribute to tumor-related immune suppression. MUC1 mediates MDSC expansion via the promotion of c-myc expression in secreted extracellular vesicles.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/13/1791/1399260/blood730614.pdf

Reference52 articles.

1. Microenvironmental regulation of therapeutic response in cancer;Klemm;Trends Cell Biol,2015

2. Clinical significance of Treg cell frequency in acute myeloid leukemia;Yang;Int J Hematol,2013

3. Coordinated regulation of myeloid cells by tumours;Gabrilovich;Nat Rev Immunol,2012

4. Tumor-induced CD14(+)HLA-DR (-/low) myeloid-derived suppressor cells correlate with tumor progression and outcome of therapy in multiple myeloma patients;Wang;Cancer Immunol Immunother,2015

Cited by 138 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. S100A4 mediates the accumulation and functions of myeloid-derived suppressor cells via GP130/JAK2/STAT3 signaling in acute myeloid leukemia;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2025-01

2. Myeloid-derived suppressor cells in cancer: Current knowledge and future perspectives;International Immunopharmacology;2024-12

3. Myeloid-derived suppressor cells: Implication in myeloid malignancies and immunotherapy;Acta Histochemica;2024-10

4. Immune‐dysregulation harnessing in myeloid neoplasms;Cancer Medicine;2024-09

5. Therapeutic targeting of PARP with immunotherapy in acute myeloid leukemia;Frontiers in Pharmacology;2024-08-08