CLEC-2 expression is maintained on activated platelets and on platelet microparticles-Reference-Cited by-同舟云学术

CLEC-2 expression is maintained on activated platelets and on platelet microparticles

Published:2014-10-02 Issue:14 Volume:124 Page:2262-2270
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Gitz Eelo¹,Pollitt Alice Y.¹,Gitz-Francois Jerney J.¹,Alshehri Osama¹,Mori Jun¹,Montague Samantha¹²,Nash Gerard B.¹²,Douglas Michael R.³⁴,Gardiner Elizabeth E.⁵,Andrews Robert K.⁵,Buckley Christopher D.³,Harrison Paul³,Watson Steve P.¹²

Affiliation:

1. Centre for Cardiovascular Sciences, College of Medical and Dental Sciences,

2. National Institute for Health Research Surgical Reconstruction and Microbiology Research Centre, and

3. School of Immunity and Infection, University of Birmingham, Birmingham, United Kingdom;

4. Department of Neurology, Dudley Group National Health Service Foundation Trust, Dudley, United Kingdom; and

5. Australian Centre for Blood Diseases, Monash University, Melbourne, Australia

Abstract

Key Points CLEC-2 activation induces proteolytic cleavage of GPVI and FcγRIIa but not itself. CLEC-2 but not GPVI is detected on platelet-derived microparticles.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/14/2262/1379663/2262.pdf

Reference64 articles.

1. Arterial thrombosis—insidious, unpredictable and deadly.;Jackson;Nat Med,2011

2. Platelets at work in primary hemostasis.;Broos;Blood Rev,2011

3. The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: a transgenic mouse model.;McKenzie;J Immunol,1999

4. CalDAG-GEFI deficiency protects mice in a novel model of Fcγ RIIA-mediated thrombosis and thrombocytopenia.;Stolla;Blood,2011

5. Patient autoantibodies induce platelet destruction signals via raft-associated glycoprotein Ibα and Fc RIIa in immune thrombocytopenia.;Urbanus;Haematologica,2013

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