Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2, and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand-Reference-Cited by-同舟云学术

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Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2, and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand

Published:2024-01 Issue:1 Volume:22 Page:271-285
ISSN:1538-7836
Container-title:Journal of Thrombosis and Haemostasis
language:en
Short-container-title:Journal of Thrombosis and Haemostasis

Author:

Martin Eleyna M.,Clark Joanne C.,Montague Samantha J.,Morán Luis A.,Di Ying,Bull Lily J.,Whittle Luke,Raka Florije,Buka Richard J.,Zafar Idrees,Kardeby Caroline,Slater Alexandre,Watson Steve P.

Funder

Horizon 2020

Wellcome Trust

NIHR Imperial Biomedical Research Centre

Horizon 2020 Framework Programme

Birmingham Biomedical Research Centre

H2020 Marie Skłodowska-Curie Actions

British Heart Foundation

National Institute for Health and Care Research

Publisher

Elsevier BV

Subject

Hematology

Reference52 articles.

1. Is the endogenous ligand for PEAR1 a proteoglycan: clues from the sea;Kardeby;Platelets,2021

2. Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases;Harbi;Platelets,2021

3. Functional significance of the platelet immune receptors GPVI and CLEC-2;Rayes;J Clin Invest,2019

4. Platelet FcgammaRIIA in immunity and thrombosis: adaptive immunothrombosis;Patel;J Thromb Haemost,2021

5. The platelet Fc receptor, FcgammaRIIa;Qiao;Immunol Rev,2015

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2. Corrigendum to ‘Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2 and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand’;Journal of Thrombosis and Haemostasis;2024-08

3. Purification and characterisation of the platelet-activating GPVI/FcRγ complex in SMALPs;Archives of Biochemistry and Biophysics;2024-04

4. GPVI inhibition: Advancing antithrombotic therapy in cardiovascular disease;European Heart Journal - Cardiovascular Pharmacotherapy;2024-03-07

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