Is glutamine depletion needed in ALL disease?
Author:
Affiliation:
1. KECK SCHOOL OF MEDICINE;
2. CHILDREN'S HOSPITAL LOS ANGELES
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/123/23/3532/1377912/3532.pdf
Reference10 articles.
1. The glutaminase activity of l-asparaginase is not required for anticancer activity against ASNS-negative cells.;Chan;Blood,2014
2. Asparaginases: biochemical pharmacology and modes of drug resistance.;Avramis;Anticancer Res,2012
3. Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.;Willems;Blood,2013
4. Unraveling the enigmatic mechanism of L-asparaginase II with QM/QM calculations.;Gesto;J Am Chem Soc,2013
5. A covalently bound catalytic intermediate in Escherichia coli asparaginase: crystal structure of a Thr-89-Val mutant.;Palm;FEBS Lett,1996
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