Reversion of anergy signatures in clonal CD21low B cells of mixed cryoglobulinemia after clearance of HCV viremia-Reference-Cited by-同舟云学术

Reversion of anergy signatures in clonal CD21low B cells of mixed cryoglobulinemia after clearance of HCV viremia

Published:2017-07-06 Issue:1 Volume:130 Page:35-38
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Del Padre Martina¹,Todi Laura¹,Mitrevski Milica¹,Marrapodi Ramona¹,Colantuono Stefania¹,Fiorilli Massimo¹^ORCID,Casato Milvia¹^ORCID,Visentini Marcella¹^ORCID

Affiliation:

1. Department of Clinical Medicine, Sapienza University of Rome Medical School, Rome, Italy

Abstract

Key Points Anergic features of B cells of MC rapidly reverse after eradication of HCV with DAAs. Phenotypic and functional features of virus-specific B-cell exhaustion persist for several months after HCV eradication.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/130/1/35/1401997/blood771238.pdf

Reference20 articles.

1. Hepatitis C virus drives the unconstrained monoclonal expansion of VH1-69-expressing memory B cells in type II cryoglobulinemia: a model of infection-driven lymphomagenesis;Carbonari;J Immunol,2005

2. Clonal expansion of immunoglobulin M+CD27+ B cells in HCV-associated mixed cryoglobulinemia;Charles;Blood,2008

3. Clonal expansion and functional exhaustion of monoclonal marginal zone B cells in mixed cryoglobulinemia: the yin and yang of HCV-driven lymphoproliferation and autoimmunity;Visentini;Autoimmun Rev,2013

4. B-cell receptors expressed by lymphomas of hepatitis C virus (HCV)-infected patients rarely react with the viral proteins;Ng;Blood,2014

5. Clonal B cells in patients with hepatitis C virus-associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset;Charles;Blood,2011

Cited by 26 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Vasculitides and Hepatitis C Infection;Infection and Autoimmunity;2024

2. Hepatitis C and Mixed Cryoglobulinemia: An Update;Infection and Autoimmunity;2024

3. Cryoglobulinemic vasculitis: a 2023 update;Current Opinion in Rheumatology;2023-11-01

4. Impact of treatment with direct‐acting antivirals on inflammatory markers and autoantibodies in HIV/HCV co‐infected individuals;Journal of Viral Hepatitis;2023-02-19

5. Opposite Effects of mRNA-Based and Adenovirus-Vectored SARS-CoV-2 Vaccines on Regulatory T Cells: A Pilot Study;Biomedicines;2023-02-10