Lysophosphatidic acid converts monocytes into macrophages in both mice and humans-Reference-Cited by-同舟云学术

Lysophosphatidic acid converts monocytes into macrophages in both mice and humans

Published:2017-03-02 Issue:9 Volume:129 Page:1177-1183
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Ray Rashmi¹²^ORCID,Rai Vivek¹^ORCID

Affiliation:

1. Department of Infectious Disease Biology, Institute of Life Sciences (An Autonomous Institute of Department of Biotechnology New Delhi), Bhubaneswar, India; and

2. School of Life Sciences, Manipal University, Manipal, Karnataka, India

Abstract

Key Points LPA converts monocytes into macrophages. LPA mediates macrophage formation via Akt/mTor pathway; PPARγ is a master regulator of LPA-derived macrophages.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/9/1177/1402493/blood743757.pdf

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4. C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages;Hoeffel;Immunity,2015

5. Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation;Jenkins;Science,2011

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