The cumulative burden of double-stranded DNA virus detection after allogeneic HCT is associated with increased mortality-Reference-Cited by-同舟云学术

The cumulative burden of double-stranded DNA virus detection after allogeneic HCT is associated with increased mortality

Published:2017-04-20 Issue:16 Volume:129 Page:2316-2325
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Hill Joshua A.¹²^ORCID,Mayer Bryan T.³,Xie Hu³,Leisenring Wendy M.³,Huang Meei-Li⁴,Stevens-Ayers Terry²,Milano Filippo³,Delaney Colleen³,Sorror Mohamed L.³,Sandmaier Brenda M.¹³,Nichols Garrett⁵,Zerr Danielle M.⁶,Jerome Keith R.²⁴,Schiffer Joshua T.¹²,Boeckh Michael¹²

Affiliation:

1. Department of Medicine, University of Washington, Seattle, WA;

2. Vaccine and Infectious Disease Division and

3. Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA;

4. Department of Laboratory Medicine, University of Washington, Seattle, WA;

5. Chimerix Inc., Durham, NC; and

6. Seattle Children’s Research Institute, Seattle, WA

Abstract

Key PointsWe demonstrate frequent plasma detection of multiple double-stranded DNA viruses after allogeneic hematopoietic cell transplantation. There was a dose-response relationship of the cumulative burden of virus exposure with early (days 0-100) and late (days 101-365) mortality.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/16/2316/1400096/blood748426.pdf

Reference41 articles.

1. Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective;Tomblyn;Biol Blood Marrow Transplant,2009

2. The burden of bacterial and viral infections in hematopoietic stem cell transplant;Kontoyiannis;Biol Blood Marrow Transplant,2009

3. Patient, virus, and treatment-related risk factors in pediatric adenovirus infection after stem cell transplantation: results of a routine monitoring program;Mynarek;Biol Blood Marrow Transplant,2014

4. EBV-induced post transplant lymphoproliferative disorders: a persisting challenge in allogeneic hematopoetic SCT;Rasche;Bone Marrow Transplant,2014

5. BK virus disease after allogeneic stem cell transplantation: a cohort analysis;Rorije;Biol Blood Marrow Transplant,2014

Cited by 138 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Final outcomes from a phase 2 trial of posoleucel in allogeneic hematopoietic cell transplant recipients;Blood Advances;2024-09-10

2. Prophylactic VSTs: a promising start but still work to do;Blood Advances;2024-09-10

3. Pitfalls in definitions on respiratory viruses and particularities of Adenovirus infection in hematopoietic cell transplantation patients: Recommendations from the EBMT practice harmonization and guidelines committee;Current Research in Translational Medicine;2024-09

4. Human herpesvirus 6 reactivation and disease are infrequent in chimeric antigen receptor T-cell therapy recipients;Blood;2024-08-01

5. Human herpesvirus 6 and CAR T-cell toxicity;Blood;2024-08-01