Essential control of early B-cell development by Mef2 transcription factors-Reference-Cited by-同舟云学术

Essential control of early B-cell development by Mef2 transcription factors

Published:2016-02-04 Issue:5 Volume:127 Page:572-581
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Herglotz Julia¹,Unrau Ludmilla¹,Hauschildt Friderike¹,Fischer Meike¹,Kriebitzsch Neele¹,Alawi Malik²³,Indenbirken Daniela²,Spohn Michael²,Müller Ursula¹,Ziegler Marion¹,Schuh Wolfgang⁴,Jäck Hans-Martin⁴,Stocking Carol¹

Affiliation:

1. Retroviral Pathogenesis and

2. Virus Genomics, Heinrich-Pette-Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany;

3. Bioinformatics Service Facility, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; and

4. Division of Molecular Immunology, Department of Internal Medicine III, Nikolaus-Fiebiger-Center, University of Erlangen-Nürnberg, Erlangen, Germany

Abstract

Key Points Mef2c and Mef2d are activated by the pre-B-cell receptor and are essential for pre-B-cell transition. Mef2c complexes with B-cell transcription factors to shut down the immediate early response and to initiate a new transcriptional network.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/5/572/1394780/572.pdf

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