Runx1 is essential at two stages of early murine B-cell development-Reference-Cited by-同舟云学术

Runx1 is essential at two stages of early murine B-cell development

Published:2013-07-18 Issue:3 Volume:122 Page:413-423
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Niebuhr Birte¹,Kriebitzsch Neele¹,Fischer Meike¹,Behrens Kira¹,Günther Thomas²,Alawi Malik²³,Bergholz Ulla¹,Müller Ursula¹,Roscher Susanne¹,Ziegler Marion¹,Buchholz Frank⁴,Grundhoff Adam²,Stocking Carol¹

Affiliation:

1. Molecular Pathology and

2. Virus Genomics, Heinrich-Pette-Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany;

3. Bioinformatics Service Facility, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; and

4. University Cancer Center, University of Technology Dresden, Dresden, Germany

Abstract

Key Points Runx1 is necessary for survival and development of B cell–specified progenitors and also the transition through the pre-B-cell stage. Genomewide expression and Runx1 occupancy analyses identified critical target genes and collaborating transcription partners.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/3/413/1372498/413.pdf

Reference51 articles.

1. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.;Mullighan;Nature,2007

2. Disruption of differentiation in human cancer: AML shows the way.;Tenen;Nat Rev Cancer,2003

3. The role of E2A-PBX1 in leukemogenesis.;Aspland;Oncogene,2001

4. Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray.;Kawamata;Proc Natl Acad Sci USA,2008

5. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.;Mullighan;N Engl J Med,2009

Cited by 48 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of Gene Regulatory Networks in B-Cell Progenitor Differentiation and Leukemia;Genes;2024-07-24

2. The role of antibody glycosylation in autoimmune and alloimmune kidney diseases;Nature Reviews Nephrology;2024-07-03

3. Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms;Nature Immunology;2023-08-10

4. Twelve Years of Genome-Wide Association Studies of Human Protein N-Glycosylation;Engineering;2023-07

5. NONO regulates B‐cell development and B‐cell receptor signaling;The FASEB Journal;2023-03-11