Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia-Reference-Cited by-同舟云学术

Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia

Published:2018-03-01 Issue:9 Volume:131 Page:1012-1021
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Guilliams Kristin P.¹²^ORCID,Fields Melanie E.²,Ragan Dustin K.¹,Eldeniz Cihat³,Binkley Michael M.⁴,Chen Yasheng¹^ORCID,Comiskey Liam S.¹,Doctor Allan²^ORCID,Hulbert Monica L.²^ORCID,Shimony Joshua S.³^ORCID,Vo Katie D.³^ORCID,McKinstry Robert C.³^ORCID,An Hongyu³^ORCID,Lee Jin-Moo¹³^ORCID,Ford Andria L.¹^ORCID

Affiliation:

1. Department of Neurology,

2. Department of Pediatrics, and

3. Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO; and

4. Department of Mechanical Engineering and Material Science, Washington University in St. Louis, St. Louis, MO

Abstract

Key Points Exchange transfusions lower global CBF and OEF in SCA, suggesting transfusions reduce infarct risk by relieving cerebral metabolic stress. In SCA, OEF is highest in the deep white matter, where infarct risk is high; transfusions reduce the volume of tissue with elevated OEF.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/131/9/1012/1406622/blood789842.pdf

Reference66 articles.

1. Stroke in children and sickle-cell disease: Baltimore-Washington Cooperative Young Stroke Study;Earley;Neurology,1998

2. Cerebrovascular accidents in sickle cell disease: rates and risk factors;Ohene-Frempong;Blood,1998

3. Effect of transfusion therapy on arteriographic abnormalities and on recurrence of stroke in sickle cell disease;Russell;Blood,1984

4. Risk of recurrent stroke in children with sickle cell disease receiving blood transfusion therapy for at least five years after initial stroke;Scothorn;J Pediatr,2002

5. Cognitive screening examinations for silent cerebral infarcts in sickle cell disease;DeBaun;Neurology,1998

Cited by 78 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Neurovascular Manifestations of Sickle Cell Disease;Hemato;2024-08-09

2. Quantitative BOLD (qBOLD) imaging of oxygen metabolism and blood oxygenation in the human body: A scoping review;Magnetic Resonance in Medicine;2024-07-28

3. Non-invasive optical and laboratory hematologic biomarkers correlate in patients with sickle cell disease;Biomedical Optics Express;2024-07-26

4. Unexpected Death of a Sickle Cell Disease Patient: A Case Report and Literature Review;Cureus;2024-06-18

5. Reversibility of Cognitive Deficits and Functional Connectivity With Transfusion in Children With Sickle Cell Disease;Neurology;2024-05-28