Autoimmune HIT due to apheresis catheter heparin flushes for stem cell harvesting before autotransplantation for myeloma

Author:

Mian Hira1,Warkentin Theodore E.23ORCID,Sheppard Jo-Ann I.3,MacDonald Anna4,Linkins Lori-Ann2,Benger Ann12,Foley Ronan123

Affiliation:

1. Department of Oncology,

2. Department of Medicine, and

3. Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada; and

4. Hamilton Regional Laboratory Medicine Program, Hamilton, ON, Canada

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference25 articles.

1. Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis. A retrospective analysis of 408 patients;Greinacher;Thromb Haemost,2005

2. Heparin-independent, PF4-dependent binding of HIT antibodies to platelets: implications for HIT pathogenesis;Padmanabhan;Blood,2015

3. Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia;Cines;Blood Adv,2016

4. The incidence of recognized heparin-induced thrombocytopenia in a large, tertiary care teaching hospital;Smythe;Chest,2007

5. Frequency of heparin-induced thrombocytopenia;Linkins,2013

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