NEDD8 and HDACs: promising cotargets in AML
Author:
Affiliation:
1. THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/127/18/2168/1392796/2168.pdf
Reference10 articles.
1. The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR.;Zhou;Blood,2016
2. NEDD8 pathways in cancer, sine quibus non.;Watson;Cancer Cell,2011
3. Ubiquitylation, neddylation and the DNA damage response.;Brown;Open Biol,2015
4. Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy.;Zhao;Antioxid Redox Signal,2014
5. Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia.;Swords;Blood,2010
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