Activation of the endomitotic spindle assembly checkpoint and thrombocytopenia in Plk1-deficient mice
Author:
Affiliation:
1. Cell Division and Cancer Group, Centro Nacional de Investigaciones Oncológicas, Madrid, Spain
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/126/14/1707/1389237/1707.pdf
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3. Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling.;Lordier;Blood,2008
4. Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes.;Gao;Dev Cell,2012
5. Polyploidy: occurrence in nature, mechanisms, and significance for the megakaryocyte-platelet system.;Zimmet;Exp Hematol,2000
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