Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans-Reference-Cited by-同舟云学术

Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans

Published:2013-09-26 Issue:13 Volume:122 Page:2205-2212
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Westera Liset¹,Drylewicz Julia¹²,den Braber Ineke¹,Mugwagwa Tendai²,van der Maas Iris¹,Kwast Lydia¹,Volman Thomas¹,van de Weg-Schrijver Elise H. R.¹,Bartha István²³⁴⁵,Spierenburg Gerrit¹,Gaiser Koos¹,Ackermans Mariëtte T.⁶,Asquith Becca⁷,de Boer Rob J.²,Tesselaar Kiki¹,Borghans José A. M.¹

Affiliation:

1. Laboratory for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands;

2. Theoretical Biology & Bioinformatics, Department of Biology, Utrecht University, Utrecht, The Netherlands;

3. Institute of Biology, Eötvös Loránd University, Budapest, Hungary;

4. School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland;

5. Institute of Microbiology, University Hospital and University of Lausanne, Lausanne, Switzerland;

6. Department of Clinical Chemistry, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and

7. Department of Immunology, Imperial College, London, United Kingdom

Abstract

Key Points Life span estimates can be sensitive to the duration of stable isotope label administration, explaining discrepancies in the literature. Multiexponential models are needed to obtain reliable leukocyte life span estimates.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/13/2205/1368415/2205.pdf

Reference22 articles.

1. Lymphocyte kinetics in health and disease.;Asquith;Trends Immunol,2009

2. Quantification of T-cell dynamics: from telomeres to DNA labeling.;Borghans;Immunol Rev,2007

3. Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection.;Hellerstein;J Clin Invest,2003

4. In vivo dynamics of stable chronic lymphocytic leukemia inversely correlate with somatic hypermutation levels and suggest no major leukemic turnover in bone marrow.;van Gent;Cancer Res,2008

5. Measurement of cell proliferation by heavy water labeling.;Busch;Nat Protoc,2007

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