Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation-Reference-Cited by-同舟云学术

Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation

Published:2014-01-23 Issue:4 Volume:123 Page:570-581
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Alvarez-Dominguez Juan R.¹²,Hu Wenqian¹,Yuan Bingbing¹,Shi Jiahai¹,Park Staphany S.¹²³,Gromatzky Austin A.¹⁴,Oudenaarden Alexander van²⁵⁶⁷,Lodish Harvey F.¹²⁴

Affiliation:

1. Whitehead Institute for Biomedical Research, Cambridge, MA;

2. Department of Biology,

3. Department of Electrical Engineering and Computer Science,

4. Department of Biological Engineering, and

5. Department of Physics, Massachusetts Institute of Technology, Cambridge, MA;

6. Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands; and

7. University Medical Center Utrecht, Utrecht, The Netherlands

Abstract

Key Points Global lncRNA discovery reveals novel erythroid-specific lncRNAs that are dynamically expressed and targeted by GATA1, TAL1, and KLF1. Multiple types of lncRNAs promote red cell maturation by regulating neighboring loci, including DLEU2 and a novel Band 3 enhancer lncRNA.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/4/570/1378717/570.pdf

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