Immunoregulatory roles of versican proteolysis in the myeloma microenvironment-Reference-Cited by-同舟云学术

Immunoregulatory roles of versican proteolysis in the myeloma microenvironment

Published:2016-08-04 Issue:5 Volume:128 Page:680-685
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Hope Chelsea¹²,Foulcer Simon³,Jagodinsky Justin¹²,Chen Sarah X.¹²,Jensen Jeffrey L.¹²,Patel Sanjay⁴,Leith Catherine⁴,Maroulakou Ioanna⁵,Callander Natalie¹²,Miyamoto Shigeki⁶,Hematti Peiman¹²,Apte Suneel S.³,Asimakopoulos Fotis¹²

Affiliation:

1. Division of Hematology/Oncology, Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI;

2. University of Wisconsin Carbone Cancer Center, Madison, WI;

3. Department of Biomedical Engineering, Cleveland Clinic Lerner Research Institute, Cleveland Clinic, Cleveland, OH;

4. Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI;

5. Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece; and

6. Department of Oncology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI

Abstract

Key Points Interplay between myeloma niche stromal cells and myeloid cells generates versikine, a novel damage-associated molecular pattern. Versikine may promote antigen-presenting cell maturation and CD8+ T-cell activation/recruitment to the tumor bed.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/128/5/680/1397666/680.pdf

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4. Versican and its associated molecules: potential diagnostic markers for multiple myeloma.;Gupta;Clin Chim Acta,2015

5. The multiple, complex roles of versican and its proteolytic turnover by ADAMTS proteases during embryogenesis.;Nandadasa;Matrix Biol,2014

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