A novel flow cytometry–based platelet aggregation assay-Reference-Cited by-同舟云学术

A novel flow cytometry–based platelet aggregation assay

Published:2013-03-07 Issue:10 Volume:121 Page:e70-e80
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

De Cuyper Iris M.¹,Meinders Marjolein¹,van de Vijver Edith¹²,de Korte Dirk¹,Porcelijn Leendert³,de Haas Masja⁴,Eble Johannes A.⁵,Seeger Karl⁶,Rutella Sergio⁷,Pagliara Daria⁷,Kuijpers Taco W.¹²,Verhoeven Arthur J.¹,van den Berg Timo K.¹,Gutiérrez Laura¹

Affiliation:

1. Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, and

2. Emma Children’s Hospital, Academic Medical Center, University of Amsterdam, The Netherlands;

3. Department of Thrombo/Leukocyte Serology, and

4. Department of Erythrocyte Serology, Sanquin Diagnostics, Amsterdam, The Netherlands;

5. Center for Molecular Medicine, Department of Vascular Matrix Biology, Excellence Cluster Cardio-Pulmonary System, Frankfurt University Hospital, Frankfurt am Main, Germany;

6. Department of Pediatric Oncology/Hematology, Otto-Heubner-Center for Pediatric and Adolescent Medicine, Charité-Universitätsmedizin, Berlin, Germany; and

7. Department of Pediatric Hematology/Oncology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Abstract

Key PointsFCA is a novel flow cytometry–based platelet aggregation assay that allows single receptor analysis in small volume/thrombocytopenic samples FCA facilitates platelet studies in experimental animal models even during gestation and allows kinetic measurements in individual animals

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/10/e70/1363848/e70.pdf

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