Paraoxonase-2 regulates coagulation activation through endothelial tissue factor-Reference-Cited by-同舟云学术

Paraoxonase-2 regulates coagulation activation through endothelial tissue factor

Published:2018-05-10 Issue:19 Volume:131 Page:2161-2172
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Ebert Julia¹²,Wilgenbus Petra¹²,Teiber John F.³,Jurk Kerstin¹,Schwierczek Kathrin¹,Döhrmann Mareike¹,Xia Ning²,Li Huige²,Spiecker Lisa²,Ruf Wolfram¹⁴,Horke Sven¹²

Affiliation:

1. Center for Thrombosis and Hemostasis and

2. Department of Pharmacology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany;

3. Division of Epidemiology, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX; and

4. Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA

Abstract

Key Points Loss of antioxidative PON2 causes cardiovascular dysfunction and activates coagulation. PON2 predominantly controls redox-sensitive endothelial TF-activation pathways.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/131/19/2161/1468320/blood807040.pdf

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5. Insights into the redox control of blood coagulation: role of vascular NADPH oxidase-derived reactive oxygen species in the thrombogenic cycle;Herkert;Antioxid Redox Signal,2004

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