Hydroxyurea reduces infections in children with sickle cell anemia in Uganda-Reference-Cited by-同舟云学术

Hydroxyurea reduces infections in children with sickle cell anemia in Uganda

Published:2024-04-04 Issue:14 Volume:143 Page:1425-1428
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Namazzi Ruth¹²,Bond Caitlin³,Conroy Andrea L.³,Datta Dibyadyuti³^ORCID,Tagoola Abner⁴,Goings Michael J.³,Jang Jeong Hoon⁵^ORCID,Ware Russell E.⁶^ORCID,Opoka Robert²,John Chandy C.³^ORCID

Affiliation:

1. 1Department of Pediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda

2. 2Global Health Uganda, Kampala, Uganda

3. 3Department of Pediatrics, Ryan White Center for Pediatric Infectious Disease and Global Health, Indiana University School of Medicine, Indianapolis, IN

4. 4Department of Pediatrics, Jinja Regional Referral Hospital, Jinja, Uganda

5. 5Underwood International College and Department of Applied Statistics, Yonsei University, Seoul, Korea

6. 6Division of Hematology, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

Abstract

Abstract After starting hydroxyurea treatment, Ugandan children with sickle cell anemia had 60% fewer severe or invasive infections, including malaria, bacteremia, respiratory tract infections, and gastroenteritis, than before starting hydroxyurea treatment (incidence rate ratio, 0.40 [95% confidence interval, 0.29-0.54]; P < .001).

Publisher

American Society of Hematology

Link

https://ashpublications.org/blood/article-pdf/143/14/1425/2219819/blood_bld-2023-021575-main.pdf

Reference22 articles.

1. Clinical analysis of mortality in hospitalized Zambian children with sickle cell anaemia;Athale;East Afr Med J,1994

2. Global burden of sickle cell anaemia in children under five, 2010-2050: modelling based on demographics, excess mortality, and interventions;Piel;PLoS Med,2013

3. The role of malaria in vaso-occlusive crisis of adult patients with sickle cell disease;Bolarinwa;J Med Med Sci,2010

4. Malaria, clinical features and acute crisis in children suffering from sickle cell disease in resource-limited settings: a retrospective description of 90 cases;Aloni;Pathog Glob Health,2013

5. Causes and outcomes of the acute chest syndrome in sickle cell disease;Vichinsky;N Engl J Med,2000

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Exploring Healthcare Utilization Events towards PalliativeTherapy in Sickle Cell Anemia;International Journal of Innovative Science and Research Technology (IJISRT);2024-06-21

2. Spleen tyrosine kinase inhibition mitigates hemin-induced thromboinflammation in the lung and kidney of sickle cell mice;2024-05-07

3. Glad tidings and joy for children with SCA;Blood;2024-04-04