TLR8 gain of function: a tall surprise
Author:
Affiliation:
1. Rockefeller University;
2. Paris University;
3. Imagine Institute;
4. Necker Hospital for Sick Children;
5. Howard Hughes Medical Institute
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/137/18/2420/1806510/bloodbld2020010463c.pdf
Reference10 articles.
1. Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function;Aluri;Blood,2021
2. Genetic analysis of resistance to viral infection;Beutler;Nat Rev Immunol,2007
3. TLR8: No gain, no pain;Barrat;J Exp Med,2018
4. Immunological loss-of-function due to genetic gain-of-function in humans: autosomal dominance of the third kind;Boisson;Curr Opin Immunol,2015
5. Self-awareness: nucleic acid-driven inflammation and the type I interferonopathies;Uggenti;Annu Rev Immunol,2019
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