Characterization of reverse-engineered anti-PF4 stereotypic antibodies derived from serum of patients with VITT

Author:

Wang Jing Jing12ORCID,van der Neut Kolfschoten Marijn3,Rutten Lucy3ORCID,Armour Bridie12ORCID,Tan Chee Wee456ORCID,Chataway Tim7ORCID,Bos Rinke3,Koornneef Annemart3,Abeywickrema Pravien8,Kapur Rick9ORCID,Porcelijn Leendert10,Khalifa Midia3,Sadi Ava3,Bouchier Pascale3ORCID,Kourkouta Eleni3,Perkasa Aditya3,Kwaks Ted3,Zahn Roland3ORCID,Solforosi Laura3ORCID,Gordon Tom P.12ORCID

Affiliation:

1. 1Department of Immunology, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia

2. 2Department of Immunology, SA Pathology, Flinders Medical Centre, Bedford Park, SA, Australia

3. 3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands

4. 4Department of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia

5. 5Department of Hematology, SA Pathology, Adelaide, SA, Australia

6. 6Department of Hematology, Royal Adelaide Hospital, Central Area Local Health Network, Adelaide, SA, Australia

7. 7Flinders Proteomics Facility, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia

8. 8Structural & Protein Sciences, Janssen Research and Development, Spring House, PA

9. 9Sanquin Research, Department of Experimental Immunohematology, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

10. 10Department of Immunohematology Diagnostics, Sanquin Diagnostic Services, Amsterdam, The Netherlands

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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