It is more “unbalanced” than you think
Author:
Affiliation:
1. 1Telethon Kids Institute
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
https://ashpublications.org/blood/article-pdf/141/10/1095/2037353/blood_bld-2022-019194-c-main.pdf
Reference10 articles.
1. RUNX1 isoform disequilibrium promotes the development of trisomy 21–associated myeloid leukemia;Gialesaki;Blood,2023
2. Haematopoietic development and leukaemia in Down syndrome;Roberts;Br J Haematol,2014
3. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome;Wechsler;Nat Genet,2002
4. Mechanisms of progression of myeloid preleukemia to transformed myeloid leukemia in children with Down syndrome;Labuhn;Cancer Cell,2019
5. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome;Malinge;J Clin Invest,2012
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