Is rapamycin a rapalog?
Author:
Affiliation:
1. Novartis Institutes for Biomedical Research, Cambridge, MA, USA
2. Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA
Publisher
IOS Press
Subject
Nutrition and Dietetics,Biochemistry,Medicine (miscellaneous),Food Science
Reference14 articles.
1. Rapamycin: An InhibiTOR of aging emerges from the soil of easter Island;Arriola Apelo;J Gerontol A Biol Sci Med Sci.,2016
2. Intermittent administration of rapamycin extends the life span of female C57BL/6J mice;Arriola Apelo;J Gerontol A Biol Sci Med Sci.,2016
3. Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction;Miller;Aging Cell,2014
4. Bitto A , Ito TK , Pineda VV , LeTexier NJ , Huang HZ , Sutlief E , et al. Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice. eLife. 2016;5.
5. Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival;Ramos;Sci Transl Med.,2012
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2. Mammalian target of rapamycin (mTOR) signaling pathway and traumatic brain injury: A novel insight into targeted therapy;Cell Biochemistry and Function;2022-03-08
3. Next Generation Strategies for Geroprotection via mTORC1 Inhibition;The Journals of Gerontology: Series A;2019-02-22
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