Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction-Reference-Cited by-同舟云学术

Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Published:2014-02-09 Issue:3 Volume:13 Page:468-477
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Miller Richard A.¹,Harrison David E.²,Astle Clinton M.²,Fernandez Elizabeth³,Flurkey Kevin²,Han Melissa¹,Javors Martin A.⁴,Li Xinna¹,Nadon Nancy L.⁵,Nelson James F.⁶,Pletcher Scott⁷,Salmon Adam B.⁸,Sharp Zelton Dave⁸⁹,Van Roekel Sabrina¹,Winkleman Lynn¹,Strong Randy³⁸

Affiliation:

1. Department of Pathology and Geriatrics Center University of Michigan Ann Arbor MI 48109 USA

2. The Jackson Laboratory Bar Harbor ME 04609 USA

3. Geriatric Research Education and Clinical Center and Research Service South Texas Veterans Health Care System San Antonio TX 78229 USA

4. Department of Psychiatry The University of Texas Health Science Center at San Antonio San Antonio TX 78229 USA

5. Division of Aging Biology National Institute on Aging Bethesda MD 20892 USA

6. Department of Physiology and Barshop Institute for Longevity and Aging Studies The University of Texas Health Science Center at San Antonio San Antonio TX 78229 USA

7. Department of Molecular and Integrative Physiology and Geriatrics Center University of Michigan Ann Arbor MI 48109 USA

8. Barshop Institute for Longevity and Aging Studies University of Texas Health Science Center San Antonio San Antonio TX 78245 USA

9. Department of Molecular Medicine University of Texas Health Science Center San Antonio San Antonio TX 78245 USA

Publisher

Wiley

Subject

Cell Biology,Aging

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.12194

Reference46 articles.

1. Gender-specific alterations in gene expression and loss of liver sexual dimorphism in the long-lived Ames dwarf mice

2. Rapamycin Extends Maximal Lifespan in Cancer-Prone Mice