N-Terminal Fragments of Huntingtin Longer than Residue 170 form Visible Aggregates Independently to Polyglutamine Expansion-Reference-Cited by-同舟云学术

N-Terminal Fragments of Huntingtin Longer than Residue 170 form Visible Aggregates Independently to Polyglutamine Expansion

Published:2017-03-28 Issue:1 Volume:6 Page:79-91
ISSN:1879-6397
Container-title:Journal of Huntington's Disease
language:
Short-container-title:JHD

Author:

Chen Moore Z.¹,Mok Sue-Ann²,Ormsby Angelique R.¹,Muchowski Paul J.³,Hatters Danny M.¹

Affiliation:

1. Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, VIC, Australia

2. Department of Neurology, University of California San Francisco, San Francisco, CA, USA

3. KynuRex, 634 Los Palmos Drive, San Francisco, CA, USA

Publisher

IOS Press

Subject

Cellular and Molecular Neuroscience,Clinical Neurology

Reference52 articles.

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3. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation;Davies;Cell,1997

4. Transgenic rat model of Huntington’s disease;von Hörsten;Hum Mol Genet,2003

5. Towards a transgenic model of Huntington/’s disease in a non-human primate;Yang;Nature,2008

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2. Mutant Huntingtin Protein Interaction Map Implicates Dysregulation of Multiple Cellular Pathways in Neurodegeneration of Huntington’s Disease;Journal of Huntington's Disease;2022-08-30

3. A New Chemoenzymatic Semisynthetic Approach Provides Insight into the Role of Phosphorylation beyond Exon1 of Huntingtin and Reveals N-Terminal Fragment Length-Dependent Distinct Mechanisms of Aggregation;Journal of the American Chemical Society;2021-06-23

4. A new chemoenzymatic semisynthetic approach provides novel insight into the role of phosphorylation beyond exon1 of Huntingtin and reveals N-terminal fragment length-dependent distinct mechanisms of aggregation;2021-03-25

5. Huntingtin protein: A new option for fixing the Huntington's disease countdown clock;Neuropharmacology;2018-06