A Proposed Brain-, Spine-, and Mental- Health Screening Methodology (NEUROSCREEN) for Healthcare Systems: Position of the Society for Brain Mapping and Therapeutics

Author:

Nami Mohammad12345,Thatcher Robert16,Kashou Nasser12,Lopes Dahabada12,Lobo Maria12,Bolanos Joe F.12,Morris Kevin12,Sadri Melody12,Bustos Teshia12,Sanchez Gilberto E.12,Mohd-Yusof Alena12,Fiallos John12,Dye Justin7,Guo Xiaofan8,Peatfield Nicholas9,Asiryan Milena12,Mayuku-Dore Alero12,Krakauskaite Solventa12,Soler Ernesto Palmero12,Cramer Steven C.10,Besio Walter G.11,Berenyi Antal12,Tripathi Manjari13,Hagedorn David14,Ingemanson Morgan14,Gombosev Marinela15,Liker Mark16,Salimpour Yousef17,Mortazavi Martin18,Braverman Eric19,Prichep Leslie S.20,Chopra Deepak21,Eliashiv Dawn S.122,Hariri Robert12232425,Tiwari Ambooj26,Green Ken12,Cormier Jason1227,Hussain Namath128,Tarhan Nevzat28,Sipple Daniel1229,Roy Michael1230,Yu John S.31,Filler Aaron13231,Chen Mike133,Wheeler Chris12,Ashford J. Wesson34,Blum Kenneth35,Zelinsky Deborah36,Yamamoto Vicky123738,Kateb Babak12394025

Affiliation:

1. Society for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA

2. Brain Mapping Foundation (BMF), Los Angeles, CA, USA

3. Neuroscience Center, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT AIP), City of Knowledge, Panama

4. Department of Neuroscience, School of Advanced Medical Sciences and Technologies, and Dana Brain Health Institute, Shiraz University of Medical Sciences, Shiraz, Iran

5. Inclusive Brain Health and BrainLabs International, Swiss Alternative Medicine, Geneva, Switzerland

6. Applied Neuroscience, Inc., St Petersburg, FL, USA

7. Department of Neurosurgery, Loma Linda University, Loma Linda, CA, USA

8. Department of Neurology, Loma Linda University, CA, USA

9. Protome Technologies Inc., Vancouver, Canada

10. Department of Neurology, UCLA, and California Rehabilitation Institute, Los Angeles, CA, USA

11. Electrical Computer and Biomedical Engineering Department and Interdisciplinary Neuroscience Program, University of Rhode Island, RI, USA

12. The Neuroscience Institute, New York University, New York, NY, USA

13. Department of Neurology, All India Institute of Medical Sciences, New Delhi, India

14. Evoke Neuroscience, New York, NY, USA

15. SPARK Neuroscience, New York, NY, USA

16. Department of Neurosurgery, Children’s Hospital Los Angeles, Los Angeles, CA, USA

17. Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA

18. California Institute of Neuroscience, Thousand Oaks, CA, USA

19. PATH Foundation NY, New York, NY, USA

20. BrainScope Inc., Bethesda, MD, USA

21. The Chopra Foundation, New York, NY, USA

22. UCLA David Geffen, School of Medicine, Department of Neurology, Los Angeles, CA, USA

23. Celularity Corporation, Warren, NJ, USA

24. Weill Cornell School of Medicine, Department of Neurosurgery, New York, NY, USA

25. Brain Technology and Innovation Park, Los Angeles, CA, USA

26. Departments of Neurology, Radiology & Neurosurgery - NYU Grossman School of Medicine, New York, NY, USA

27. Lafayette Surgical Specialty Hospital, Lafayette, LA, USA

28. Department of Psychiatry, Faculty of Medicine, Uskudar University, Turkey

29. Midwest Spine and Brain Institute, Roseville, MN, USA

30. Uniformed Services University Health Science (USUHS), Baltimore, MD, USA

31. Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA

32. Institute for Nerve Medicine, Santa Monica, CA, USA

33. Department of Neurosurgery, City of Hope Comprehensive Cancer Center, Duarte, CA, USA

34. Stanford University, Palo Alto, VA, USA

35. Division of Addiction Research, Center for Psychiatry, Medicine, and Primary Care, Western Health Sciences, Pomona, CA, USA

36. Mind-Eye Institute, Northbrook, IL, USA

37. USC Keck School of Medicine, The USC Caruso Department of Otolaryngology-Head and Neck Surgery, Los Angeles, CA, USA

38. USC-Norris Comprehensive Cancer Center, Los Angeles, CA, USA

39. Loma Linda University, Department of Neurosurgery, Loma Linda, CA, USA

40. National Center for NanoBioElectronic (NCNBE), Los Angeles, CA, USA

Abstract

The COVID-19 pandemic has accelerated neurological, mental health disorders, and neurocognitive issues. However, there is a lack of inexpensive and efficient brain evaluation and screening systems. As a result, a considerable fraction of patients with neurocognitive or psychobehavioral predicaments either do not get timely diagnosed or fail to receive personalized treatment plans. This is especially true in the elderly populations, wherein only 16% of seniors say they receive regular cognitive evaluations. Therefore, there is a great need for development of an optimized clinical brain screening workflow methodology like what is already in existence for prostate and breast exams. Such a methodology should be designed to facilitate objective early detection and cost-effective treatment of such disorders. In this paper we have reviewed the existing clinical protocols, recent technological advances and suggested reliable clinical workflows for brain screening. Such protocols range from questionnaires and smartphone apps to multi-modality brain mapping and advanced imaging where applicable. To that end, the Society for Brain Mapping and Therapeutics (SBMT) proposes the Brain, Spine and Mental Health Screening (NEUROSCREEN) as a multi-faceted approach. Beside other assessment tools, NEUROSCREEN employs smartphone guided cognitive assessments and quantitative electroencephalography (qEEG) as well as potential genetic testing for cognitive decline risk as inexpensive and effective screening tools to facilitate objective diagnosis, monitor disease progression, and guide personalized treatment interventions. Operationalizing NEUROSCREEN is expected to result in reduced healthcare costs and improving quality of life at national and later, global scales.

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

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