Transthyretin Suppresses Amyloid-β Secretion by Interfering with Processing of the Amyloid-β Protein Precursor-Reference-Cited by-同舟云学术

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Transthyretin Suppresses Amyloid-β Secretion by Interfering with Processing of the Amyloid-β Protein Precursor

Published:2016-06-07 Issue:4 Volume:52 Page:1263-1275
ISSN:1387-2877
Container-title:Journal of Alzheimer's Disease
language:
Short-container-title:JAD

Author:

Li Xinyi¹²,Song Yuanli³⁴,Sanders Charles R.⁴,Buxbaum Joel N.²

Affiliation:

1. Janssen Research & Development, LLC, Johnson & Johnson, San Diego, CA, USA

2. Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA

3. Bristol-Myers Squibb, Biologics Process Development, Devens, MA, USA

4. Department of Biochemistry and Center for Structural Biology, Vanderbilt University School of Medicine, Nashville, TN, USA

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference57 articles.

1. Interaction of transthyretin with amyloid beta-protein: Binding and inhibition of amyloid formation;Schwarzman;Ciba Found Symp,1996

2. Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways;Stein;J Neurosci,2002

3. Neuronal production of transthyretin in human and murine Alzheimer’s disease: Is it protective?;Li;J Neurosci,2011

4. The systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer’s disease model mice.;Wang;J Neurosci,2014

5. Transthyretin protects Alzheimer’s mice from the behavioral and biochemical effects of Abeta toxicity;Buxbaum;Proc Natl Acad Sci U S A,2008

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1. Tetrameric Transthyretin as a Protective Factor Against Alzheimer’s Disease;Molecular Neurobiology;2024-08-27

2. Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation;Journal of Biological Chemistry;2022-12

3. Deep blue autofluorescence reflects the oxidation state of human transthyretin;Redox Biology;2022-10

4. Hspa13 Regulates Endoplasmic Reticulum and Cytosolic Proteostasis Through Modulation of Protein Translocation;2022-06-27

5. Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling;ACS Chemical Biology;2022-06-08

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