Strikingly Reduced Amyloid Burden and Improved Behavioral Performance in Alzheimer's Disease Mice Immunized with Recombinant Chimeric Vaccines by Hexavalent Foldable Aβ1-15 Fused to Toxin-Derived Carrier Proteins
Author:
Affiliation:
1. Beijing Institute of Biotechnology, Beijing, China
2. Pharmaceutical College, Henan University, Kaifeng, China
3. Institute of Life Science and Biotechnology, Beijing Jiaotong University, Beijing, China
Publisher
IOS Press
Subject
Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience
Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Effect and Potential Mechanism of Immunotherapy on Cognitive Deficits in Animal Models of Alzheimer's Disease: A Systematic Review and Meta-Analysis;The American Journal of Geriatric Psychiatry;2023-12
2. Active Immunotherapy with 12-mer Aβ1-42-like Assembly Vaccine Shows Efficacy in Aged 3×Tg-AD Mice;Current Molecular Medicine;2021-03-18
3. Improved synaptic and cognitive function in aged 3 × Tg-AD mice with reduced amyloid-β after immunotherapy with a novel recombinant 6Aβ15-TF chimeric vaccine;Clinical Immunology;2018-08
4. Astrocytes with previous chronic exposure to amyloid -peptide fragment 1-40 suppress excitatory synaptic transmission;J NEUROCHEM;2017
5. Prophylactic immunotherapy of Alzheimer's disease using recombinant amyloid-β B-cell epitope chimeric protein as subunit vaccine;Human Vaccines & Immunotherapeutics;2016-07-05
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