Improved synaptic and cognitive function in aged 3 × Tg-AD mice with reduced amyloid-β after immunotherapy with a novel recombinant 6Aβ15-TF chimeric vaccine-Reference-Cited by-同舟云学术

Improved synaptic and cognitive function in aged 3 × Tg-AD mice with reduced amyloid-β after immunotherapy with a novel recombinant 6Aβ15-TF chimeric vaccine

Published:2018-08 Issue: Volume:193 Page:12-23
ISSN:1521-6616
Container-title:Clinical Immunology
language:en
Short-container-title:Clinical Immunology

Author:

Yu Yun-Zhou^ORCID,Li Qing-Li,Wang Hai-Chao,Liu Si,Pang Xiao-Bin,Xu Qing,Zhou Xiao-Wei,Huang Pei-Tang

Funder

Major National Science and Technology

Natural Science Foundation of Beijing

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference71 articles.

1. The role of amyloid beta in the pathogenesis of Alzheimer's disease;Gilbert;J. Clin. Pathol.,2013

2. Reassessing the amyloid cascade hypothesis of Alzheimer's disease;Pimplikar;Int. J. Biochem. Cell Biol.,2009

3. Immunotherapeutic approaches for Alzheimer's disease in transgenic mouse models;Wisniewski;Brain Struct. Funct.,2010

4. Murine models of Alzheimer's disease and their use in developing immunotherapies;Wisniewski;Biochim. Biophys. Acta,2010

5. Amyloid-β-directed immunotherapy for Alzheimer's disease;Lannfelt;J. Intern. Med.,2014

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Effect and Potential Mechanism of Immunotherapy on Cognitive Deficits in Animal Models of Alzheimer's Disease: A Systematic Review and Meta-Analysis;The American Journal of Geriatric Psychiatry;2023-12

2. DNA vaccines targeting amyloid-β oligomer ameliorate cognitive deficits of aged APP/PS1/tau triple-transgenic mouse models of Alzheimer’s disease;Neural Regeneration Research;2022

3. Targeted drug delivery systems to control neuroinflammation in central nervous system disorders;Journal of Drug Delivery Science and Technology;2021-12

4. Active Immunotherapy with 12-mer Aβ1-42-like Assembly Vaccine Shows Efficacy in Aged 3×Tg-AD Mice;Current Molecular Medicine;2021-03-18

5. Role of Kalirin and mouse strain in retention of spatial memory training in an Alzheimer’s disease model mouse line;Neurobiology of Aging;2020-11