Obtaining preparations with increased content of bioactive compounds from eight types of berries

Abstract

BACKGROUND: Cranberries, black and red currants, strawberries, chokeberries, raspberries, blueberries and blackberries, due to the high content of polyphenolic compounds, become an excellent matrix for the production of preparations that can be used as nutraceuticals. OBJECTIVE: Evaluation of the content of bioactive compounds and health-promoting activity of preparations from polyphenolic fractions isolated from eight types of berries. METHODS: The preparations were obtained by lyophilization of the polyphenolic fraction of fruit extracts, and then they were evaluated in terms of physicochemical properties, content of polyphenolic compounds and antioxidant, antidiabetic, antiobesity and anticancer activity. RESULTS: The analyzes showed a very diverse content of bioactive compounds and a high health-promoting potential significantly depending on the type of fruit. In total, 61 polyphenolic compounds were identified, with anthocyanins being the dominant group. A positive correlation was found between the content of polyphenolic compounds and high antioxidant activity. A cytotoxic effect on colorectal adenocarcinoma cells (Caco-2) was also found. In addition, all the obtained preparations turned out to be effective inhibitors of enzymes promoting diabetes and obesity. CONCLUSIONS: The obtained preparations can be used in the production of nutraceuticals or functional food additives, applicable in the prevention and treatment of lifestyle diseases.