Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases-Reference-Cited by-同舟云学术

Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases

Published:2018-07-11 Issue: Volume:14 Page:1734-1742
ISSN:1860-5397
Container-title:Beilstein Journal of Organic Chemistry
language:en
Short-container-title:Beilstein J. Org. Chem.

Author:

Kasatkina Svetlana O^ORCID,Stepanova Ekaterina E^ORCID,Dmitriev Maksim V,Mokrushin Ivan G,Maslivets Andrey N^ORCID

Abstract

Acyl(quinoxalin-2-yl)ketenes generated by thermal decarbonylation of 3-acylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones react regioselectively with Schiff bases under solvent-free conditions to form pyrimido[1,6-a]quinoxaline derivatives in good yields.

Publisher

Beilstein Institut

Subject

Organic Chemistry

Link

https://www.beilstein-journals.org/bjoc/content/pdf/1860-5397-14-147.pdf

Reference62 articles.

1. Quinoxaline, its derivatives and applications: A State of the Art review

2. Quinoxaline: An insight into the recent pharmacological advances

3. Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)

4. Quinoxalin-2(1H)-One Derivatives As Inhibitors Against Hepatitis C Virus

5. Antiobesity-like effects of the 5-HT2C receptor agonist WAY-161503

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