Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)-Reference-Cited by-同舟云学术

Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)

Published:2009-08 Issue:15 Volume:19 Page:4050-4054
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Miyashiro Julie,Woods Keith W.,Park Chang H.,Liu Xuesong,Shi Yan,Johnson Eric F.,Bouska Jennifer J.,Olson Amanda M.,Luo Yan,Fry Elizabeth H.,Giranda Vincent L.,Penning Thomas D.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors

2. PARP inhibition sensitizes p53-deficient breast cancer cells to doxorubicin-induced apoptosis

3. Chemopotentiation by PARP inhibitors in cancer therapy

4. The role of inhibitors of poly(ADP-ribose) polymerase as resistance-modifying agents in cancer therapy

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