Amitriptyline or Not, That Is the Question: Pharmacogenetic Testing of CYP2D6 and CYP2C19 Identifies Patients with Low or High Risk for Side Effects in Amitriptyline Therapy
Author:
Affiliation:
1. Institut für Klinische Chemie und Pathobiochemie and Psychiatrische Klinik und Poliklinik,
2. Klinikum rechts der Isar, Technische Universität München, Munich, Germany
3. Bezirkskrankenhaus Haar, Haar, Germany
Abstract
Publisher
Oxford University Press (OUP)
Subject
Biochemistry (medical),Clinical Biochemistry
Link
http://academic.oup.com/clinchem/article-pdf/51/2/376/32682000/clinchem0376.pdf
Reference45 articles.
1. Ustun TB. The global burden of mental disorders. Am J Public Health1999;89:1315-1318.
2. Crismon ML, Trivedi M, Pigott TA, Rush AJ, Hirschfeld RM, Kahn DA, et al. The Texas Medication Algorithm Project: report of the Texas Consensus Conference Panel on Medication Treatment of Major Depressive Disorder. J Clin Psychiatry1999;60:142-156.
3. Tucker GT. Advances in understanding drug metabolism and its contribution to variability in patient response. Ther Drug Monit2000;22:110-113.
4. Venkatakrishnan K, Greenblatt DJ, von Moltke LL, Schmider J, Harmatz JS, Shader RI. Five distinct human cytochromes mediate amitriptyline N-demethylation in vitro: dominance of CYP 2C19 and 3A4. J Clin Pharmacol1998;38:112-121.
5. Perry PJ, Zeilmann C, Arndt S. Tricyclic antidepressant concentrations in plasma: an estimate of their sensitivity and specificity as a predictor of response. J Clin Psychopharmacol1994;14:230-240.
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