Survival Is Not a Good Outcome for Randomized Trials With Effective Subsequent Therapies
Author:
Affiliation:
1. International Drug Development Institute, Louvain-la-Neuve, Belgium
2. Mayo Clinic, Rochester, MN
3. Dendrix Research, São Paulo, Brazil
Publisher
American Society of Clinical Oncology (ASCO)
Subject
Cancer Research,Oncology
Link
http://ascopubs.org/doi/pdfdirect/10.1200/JCO.2011.38.4206
Reference6 articles.
1. Overall Survival As the Outcome for Randomized Clinical Trials With Effective Subsequent Therapies
2. Assessing the Measure of a New Drug: Is Survival the Only Thing That Matters?
3. Changing End Points in Breast-Cancer Drug Approval — The Avastin Story
4. Evaluation of Tumor Response, Disease Control, Progression-Free Survival, and Time to Progression As Potential Surrogate End Points in Metastatic Breast Cancer
5. Detecting an Overall Survival Benefit that Is Derived From Progression-Free Survival
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