Phase III, randomized study of trastuzumab emtansine (T-DM1) ± pertuzumab (P) vs trastuzumab + taxane (HT) for first-line treatment of HER2-positive MBC: Primary results from the MARIANNE study.

Author:

Ellis Paul Anthony1,Barrios Carlos H.2,Eiermann Wolfgang3,Toi Masakazu4,Im Young-Hyuck5,Conte Pier Franco6,Martin Miguel7,Pienkowski Tadeusz8,Pivot Xavier B.9,Burris Howard A.10,Strasak Alexander11,Patre Monika12,Perez Edith A.13

Affiliation:

1. Guy’s Hospital and Sarah Cannon Research Institute, London, United Kingdom

2. PUCRS School of Medicine, Porto Alegre, Brazil

3. Interdisciplinary Oncology Center, Munich, Germany

4. Graduate School of Medicine, Kyoto University, Kyoto, Japan

5. Samsung Medical Center, Seoul, South Korea

6. Department of Surgery, Oncology and Gastroenterology, University of Padova and Istituto Oncologico Veneto, Padova, Italy

7. Instituto de Investigación Sanitaria Gregorio Marañón, Universidad Complutense de Madrid, Madrid, Spain

8. Postgraduate Medical Education Center, Warsaw, Poland

9. University Hospital Jean Minjoz, Besançon, France

10. Sarah Cannon Research Institute, Tennessee Oncology, PLLC, Nashville, TN

11. F. Hoffmann-La Roche Ltd, Basel, Switzerland

12. F. Hoffmann-La Roche Ltd., Basel, Switzerland

13. Mayo Clinic, Jacksonville, FL

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

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