Simultaneous determination of sulindac and its metabolites sulindac sulfide and sulindac sulfone in human plasma by a sensitive UPLC-PDA method for a pharmacokinetic study
Author:
Affiliation:
1. Department of Clinical Pharmacology
2. Xiangya Hospital
3. Central South University
4. Changsha, China
5. Institute of Clinical Pharmacology
6. School of Pharmacy
7. Hunan University of Chinese Medicine
8. The Third Affiliated Teaching Hospital
Abstract
A pharmacokinetic study of sulindac and its metabolites.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/AY/C4AY00730A
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1. Population Pharmacokinetic Model for Cancer Chemoprevention With Sulindac in Healthy Subjects
2. Synergistic induction of apoptosis by sulindac and simvastatin in A549 human lung cancer cells via reactive oxygen species-dependent mitochondrial dysfunction
3. Curcumin enhances the lung cancer chemopreventive efficacy of phospho-sulindac by improving its pharmacokinetics
4. Angiostatic Properties of Sulindac and Celecoxib in the Experimentally Induced Inflammatory Colorectal Cancer
5. Nitric oxide-releasing sulindac is a novel skin cancer chemopreventive agent for UVB-induced photocarcinogenesis
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